Audit and Inspection Support for the National Institute of Environmental Health Sciences (NIEHS)
For more than 35 years, CSS has provided quality control assessment support to the National Toxicology Program (NTP) on studies relating to the toxicological effects of chemicals in the environment.
Audit and Inspection Support for the National Institute of Environmental Health Sciences (NIEHS).
For more than 35 years – CSS’s longest running contract – we have provided quality assessment support to the National Toxicology Program (NTP) for studies carried out on their behalf by contract laboratories regarding toxicological effects of chemicals in the environment.
CSS toxicologists verify that the required and appropriate experimental procedures were followed in every detail, that observations and results were accurately and completely recorded, that the archival data and specimens were properly organized, catalogued, and maintained to facilitate access, and that the conduct of each study was described accurately, and the data presented correctly in NTP Technical Reports. Our audit reports verify whether the information contained in the NTP Technical Report is supported by the original study records submitted to the NTP Archives.
Among the types of studies audited are pre-chronic toxicity, chronic toxicity/carcinogenicity, Reproductive Assessment by Continuous Breeding (RACB), Modified One Generation (MOG), developmental toxicity (including teratological endpoints), behavioral and neurotoxicity, immunotoxicity, and toxicokinetic. Our audit tasks have recently been expanded to include draft manuscripts of research studies being prepared for publication.
Example studies include:
Bisphenol A (BPA) used to manufacture polycarbonate plastics. This type of plastic was used to make some types of beverage containers, compact disks, plastic dinnerware, impact-resistant safety equipment, automobile parts, and toys;
Radiofrequency radiation emitted by cell phones;
Polyfluoroalkyl substances (PFAS) used in an extensive number of consumer products (Teflon). These ‘forever chemicals’ are extremely resistant to degradation in the environment;
Glyphosate, the most heavily used herbicide world-wide (the active ingredient in Roundup).
Additional Projects
ITC Tank Farm Fire Emergency Response
In response to a dangerous fire EPA ordered CSS’ senior field operations specialists to a facility near Houston where massive tanks stored highly flammable liquids to help manage emergency response activities.
Coastal Aquaculture Program / Coastal Aquaculture Siting & Sustainability Program
CSS supports the NCCOS mission to provide high quality science, guidance, and technical support to coastal managers to grow sustainable aquaculture while maintaining and improving ecosystem health.
Analysis for Coastal Operational Resiliency
CSS assisted with planning and executing a demonstration of three decontamination technologies on a USCG vessel contaminated with a benign surrogate for anthrax.
Service Areas
Space Science Application Support & Operations
We deliver scientific support to advance our clients’ research goals.
Safety, Health, & Environmental
We provide our clients with tools to protect their workforce, the public, and the environment.
Facilities Operations & Maintenance
We understand your facility support needs and deliver customized solutions.
Human Health Risk Assessment
We help advance the understanding of chemical effects on people and the environment.
Environmental Resource Assessment & Management
We apply science to address challenges affecting the nation’s natural resources.
Satellite Data Applications
Helping create a more environmentally sustainable, weather-ready, and secure nation through application of earth observation data
Get in touch
Contact us to learn more about our projects, capabilities, solutions, and service offerings.